Nucleic acid — FTIR absorption peaks and assignments

Quick answer

Nucleic acid is usually assigned by looking for a recurring cluster of characteristic peaks rather than one exact textbook number. The table below shows where the literature most often places this group in FTIR, ranked by accumulated evidence.

Characteristic FTIR peaks for Nucleic acid

Showing the 30 best-supported peaks of 201 total for Nucleic acid.

Possible materials

Spectrum logic

A functional-group assignment becomes more confident when several expected bands appear together. Use this page to find the strongest-supported peaks, then confirm that the same sample exhibits a coherent pattern rather than a single isolated hit.

Real-world usage

These pages are useful for unknown material analysis, peak explanation in reports, polymer troubleshooting, and verifying whether a candidate material family is chemically plausible.

Common mistakes

• Using one functional-group page as a complete material verdict without checking the rest of the spectrum.
• Assuming the strongest band is always the most diagnostic one.
• Forgetting that processing, additives, aging, and mixtures can shift or broaden expected peaks.

Verification advice

Use DSC, GC-MS, or TGA when several material families share similar bands or when mixture effects make the FTIR assignment uncertain.

Literature behind these assignments

• 1635 cm⁻¹ confidence 1.0

  “0.1 100 1000 10000 1 10 CS-SP nanoparticle with plasmid DNA, peaks at 3249.04 and 1635.09cm-1 (d, Size nm) shifted from lower frequency wavenumbers to 1635.58cm-1”

  Bande 等 - 2015 - Synthesis and Characterization of Chitosan-Saponin DOI: 10.1155/2015/371529
• 1029 cm⁻¹ confidence 1.0

  “At the same time, this spectrum contains peaks at 1029 PO2cm-1, corresponding to from DNA, RNA and phospholipids, and 1520 which have been observed in normal breast tissues before.”

  The Spectroscopic Similarity between Breast Cancer Tissues and Lymph Nodes Obtained from Patients with and without Recurrence: A Preliminary Study DOI: 10.3390/molecules25143295
• 1320 cm⁻¹ confidence 1.0

  “It was found that with the increase of NaCl, MgCl 2, or ethanol concentration in the incm-1, cm-1, cm-1 duction solution, the characteristic Z-DNA peaks of 1320 1125 and 925 in the infrared spectra changed during the B-Z DNA transition, and”

  Assessing B-Z DNA Transitions in Solutions via Infrared Spectroscopy DOI: 10.3390/biom13060964
• 965 cm⁻¹ confidence 1.0

  “DNA-RNA I965 < I1055 < Imax and DNA-DNA interactions as were the most clearly observed in 3 BCC level DNA/RNA triad peak I965 < I1055 > Imax patients with high-leveled peaks of nucleic acids, that were presented as level DNA/RNA triad peak”

  Eikje - 2011 - DNA-RNA, DNA-DNA, DNA-protein and protein-protein DOI: 10.1117/12.874692
• 1159 cm⁻¹ confidence 1.0

  “2- (] asymmetric stretching (PO )) Nucleic acid PO as (] C-O stretching (C-O)) 1159 Protein/CarbohydrateLipid”

  Ferreira 等 - 2020 - Attenuated Total Reflection-Fourier Transform Infr DOI: 10.1155/2020/4343590
• 1306 cm⁻¹ confidence 1.0

  “1338cm(cid:2)1, 993cm(cid:2)1 which was not seen in Bacilwhich is due to nucleic acids, and the which located at that reason the peak at 1306 S.”

  Use of Fourier transform infrared spectroscopy for rapid comparative analysis of Bacillus and Micrococcus isolates DOI: 10.1016/j.foodchem.2008.08.063
• 1708 cm⁻¹ confidence 1.0

  “A similar result was obtained by Mello and Vidal [27], who suggested that FTIR spectra cm-1, 1708 and 1668 cm-1 in the region (1700-1600 cm-1) could be due to C=O stretching vibration of of bovine DNA was higher than that of fish DNA at the”

  Han 等 - 2018 - Insight into Rapid DNA-Specific Identification of DOI: 10.3390/molecules23112842
• 1661 cm⁻¹ confidence 1.0

  “1A, strong bands were cm-1, observed at 1661, 1241, 1094 and 966 which can be assigned to distinct functional groups of DNA.”

  A novel FTIR discrimination based on genomic DNA for species-specific analysis of meat and bone meal DOI: 10.1016/j.foodchem.2019.05.088